TABLE 5.2

Metal Nanomaterials Applied in LOC Devices for Various Applications and Detection Techniques

Nanomaterials-

electrode/LOC

Applications/ analyte

Types of sensors

Detection technique

Linear range

LOD

Reference

AuNP/glass-PDMS

microfluidic

Foodborne pathogens

(E. coli O157:H7)

Optical Biosensor

Colorimetric of AuNPs

aggregation and

smartphone imaging

5.0 × 101–5.0 ×

108 CFU/mL

50 CFU/mL

[ 7]

AuNPs-MWCNT/

Aptamer/microwell plate

Foodborne pathogens

(E. coli O157:H7)

Optical Biosensor

Colorimetric of AuNPs

aggregation and

smartphone imaging

–

524 cfu/mL

[ 8]

AuNPs-anti AB1

antibody/Au chip

Food Content

(Aflatoxin B1)

Optical Biosensor

Surface Plasmon

Resonance

0.01–50 nM

0.003 nM

[ 9]

AuNPs/glass-PDMS

microwell plate

Heavy Metal (Pb(II) &

Al(III))

Optical Sensor

Surface Plasmon

Resonance

0–500 ppb

0–400 ppb

30 ppb

89 ppb

[ 10]

AuNPs/ITO/Sandwich

glass slide

Heavy Metal (Hg(II))

Electrochemical Sensor

DPASV

0.63–80 ppb

0.11 ppb

[ 11]

AuNPs/Glass microchip

DNA

Optical Biosensor

Laser-induced

fluorescence (LIF)

50–500 nM

2.6 zepto mole

[ 12]

AgNPs-aptamer/glass-

PDMS microfluidic

Protein (Thrombin)

Optical Sensor

Colorimetric of AgNPs

20–5000 pM

20 pM

[ 13]

AgNPs/Chitosan/PGE

microfluidic

H2O2

Electrochemical Sensor

Cyclic Voltammetry

1–10 µM

0.52 µM

[ 14]

AgNPs-PDDA/glass-

PDMS microfluidic

Foodborne pathogens

(E. coli O157:H7)

Electrochemical

Biosensor

Impedimetric

2 × 103–2 × 105

cfu/mL

500 cfu·mL

[ 15]

PtNPs/PDMS microfluidic Vitamin B

Optical Sensor

Chemiluminescence

1.0 x 10−7–4.0 ×

10−5 mol/L

4.8 × 10−9 mol/L

[ 16]

PtNPs-HRP/BDD/PDMS

microfluidic

Pesticide (Atrazine)

Electrochemical Sensor

Chronoamperometry

0.9–4.5 nM

3 pM

[ 17]

AuNPs-PtNCs

Salmonella

Typhimurium

Optical Biosensor

Microplate reader

1.8 x 101–1.8 x 107 25

CFU/mL

17 CFU/mL

[ 18]

Abbreviation: DPASV: differential pulse anodic stripping voltammetry.

78

Bioelectronics